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Definition of Efficacy

The word “efficacy” is a term most commonly used in medicine with a specific meaning: “The extent to which a specific intervention, procedure, regimen, or service produces a beneficial result under ideal conditions“. The word applies to prescription pharmaceuticals where the claims are supported by extensive clinical studies that must pass the scrutiny of the FDA before being certified as legitimate.

In a world of products unregulated by the FDA, the word has equal meaning but potentially greater importance as to the legitimacy of product claims.

Fitness Formulary is committed to delivering products whose ingredients have efficacy and are legitimately effective in the pursuit of a fitness goal and/or the treatment or prevention of a medical condition. Our MyHealth Efficacy Engine uses graded medical evidence to provide a list of products  that have the intended effect. Consumers are empowered with the knowledge as to what to expect the results could be.

At the same time, it is important that, even in pharmacology, prescription medications may not have equal effectiveness from person to person. We rely upon the physicians, pharmacists and chemists to deliver the most likely results. Each person has her/his unique chemistry that results in the efficacy of pharmaceutical medications or those products we recommend here.

Formulary Panel Mission

The Formulary Panel is comprised of leading physicians, surgeons, pharmacists, scientists, philosophers, chemists and nutritionists focused on health, wellness, fitness and nutrition. They are responsible for authentication of the Efficacy Engine, approving sources of scientific evidence by use by the Efficacy Engine, governance and oversight. They share the ideal that prevention is the first objective in the pursuit of health and wellness and that integrative medicine and behavioral modification are key considerations in disease treatment.

Authentication of the Efficacy Engine means randomized testing of the underlying algorithms to verify that results delivered consist of products containing ingredients wherein the clinical studies support the efficacy of the ingredient shown within the subject product. The Formulary Panel does NOT have any responsibility to verify, authenticate, approve or endorse clinical studies utilized by the Efficacy Engine; it only recommends legitimate sources of medical facts to be considered for use by the Efficacy Engine.

Formulary Panel Roles

  • Authentication of the Efficacy Engine algorithm
  • Review and recommendation of sources for clinical studies
  • Brand recommendations where applicable
  • Preparation, participation and feedback in panel meetings
  • Impartiality and objectivity
  • Support and endorsement of Efficacy Engine
  • Testimonials for media and public relations
  • Advice for enhancement of the Efficacy Engine
  • Submission of practice area articles for publishing if appropriate
  • Attract and inspire other leading experts to join the Panel

Our Methodology

Our customers  are able to complete their own MyHealth Profile once registered at our website wherein they can specify their health/fitness goals, medical conditions and/or prescription/OTC drug usage. Our patent-pending methodology delivers a list of products based upon the efficacy of the ingredients in any given product in achieving health/fitness goals and/or preventing/treating medical conditions according to the clinical studies. Furthermore, our methodology eliminates any products whose ingredients are contraindicative with prescription/OTC drugs our customer is taking where the customer has completed their MyPrescription Profile.

The technology works like this in delivering the product list:

  1. Every ingredient for every product we sell is listed in a database.
  2. Our customer provides information to us in the MyHealth Assessment.
  3. Ingredients are rated using the Natural Standard methodology.
  4. Products with Ingredients ranked A, B or C are shown in descending order of relevant efficacy.
    The methodology works somewhat differently when browsing products at random through the website:
  1. Every ingredient for every product we sell is listed in a database
  2. User enters their Health Profile information
  3. Grades show up beside each product based upon the methodology described above. Products with D and F ingredients are visible as the user is browsing all products

The methodology and system are fully dependent upon our customer entering complete data and is limited to the clinical studies and efficacy ratings of ingredients currently in our database.

Our Grading System

GradeLevelDetails
AEffectiveThis product has a very high level of reliable clinical evidence supporting its use for a specific indication. Products rated Effective are generally considered appropriate to recommend. To achieve this Effectiveness Rating a product is supported by all of the following: – Evidence consistent with or equivalent to passing a review by the Food and Drug Administration (FDA), Health Canada, or similarly rigorous approval process.
– Evidence from multiple (2+) randomized clinical trials or meta-analysis including several hundred to several thousand patients (level of evidence = A).
– Studies have a low risk of bias and high level of validity by meeting stringent assessment criteria (quality rating = A).
– Evidence consistently shows POSITIVE outcomes for a given indication without valid evidence to the contrary.
BProbably EffectiveThis product has a very high level of reliable clinical evidence supporting its use for a specific indication. Products rated “Likely Effective” are generally considered appropriate to recommend. To achieve this Effectiveness Rating a product is supported by all of the following: – Evidence from multiple (2+) randomized clinical trials or meta-analysis including several hundred patients (level of evidence = A).
– Studies have a low risk of bias and high level of validity by meeting stringent assessment criteria (quality rating = A).
– Evidence consistently shows POSITIVE outcomes for a given indication without significant valid evidence to the contrary.
CMarginally EffectiveThis product has some clinical evidence supporting its use for a specific indication; however, the evidence is limited by quantity, quality, or contradictory findings. Products rated “Possibly Effective” might be beneficial, but do not have enough high-quality evidence to recommend for most people. To achieve this Effectiveness Rating a product is supported by all of the following: – One or more randomized clinical trials or meta-analysis (level of evidence = A or B) or two or more population based or epidemiological studies (level of evidence = B).
– Studies have a low to moderate risk of bias and moderate to high level of validity by meeting or partially meeting assessment criteria (quality rating A or B).
– Evidence shows POSITIVE outcomes for a given indication without substantial valid evidence to the contrary. Some contrary evidence may exist; however, valid positive evidence outweighs contrary evidence.
DPossibly IneffectiveThis product has some clinical evidence showing ineffectiveness for a specific indication; however, the evidence is limited by quantity, quality, or contradictory findings. People should be advised NOT to take products with a “Possibly Ineffective” rating. To achieve this Effectiveness Rating a product is supported by all of the following: – One or more randomized clinical trials or meta-analysis (level of evidence = A or B) or two or more population based or epidemiological studies (level of evidence = B).
– Studies have a low to moderate risk of bias and moderate to high level of validity by meeting or partially meeting assessment criteria (quality rating A or B).
– Evidence shows NEGATIVE outcomes for a given indication without substantial valid evidence to the contrary. Some contrary evidence may exist; however, valid positive evidence outweighs contrary evidence.
EProbably IneffectiveThis product has a very high level of reliable clinical evidence showing ineffectiveness for its use for a specific indication. People should be discouraged from taking products with a “Likely Ineffective” rating. To achieve this Effectiveness Rating a product is supported by all of the following: – Evidence from multiple (2+) randomized clinical trials or meta-analysis including several hundred patients (level of evidence = A).
– Studies have a low risk of bias and high level of validity by meeting stringent assessment criteria (quality rating = A).
– Evidence consistently shows NEGATIVE outcomes for a given indication without significant valid evidence to the contrary.
FIneffective / HazardousThis product has a very high level of reliable clinical evidence showing ineffectiveness for its use for a specific indication. People should be discouraged from taking products with an “Ineffective” rating. To achieve this Effectiveness Rating a product is supported by all of the following: – Evidence from multiple (2+) randomized clinical trials or meta-analysis including several hundred to several thousand patients (level of evidence = A).
– Studies have a low risk of bias and high level of validity by meeting stringent assessment criteria (quality rating = A).
– Evidence consistently shows NEGATIVE outcomes for a given indication without valid evidence to the contrary.